Seven American Cheese Slices Made with Genuine Cheese
American cheese gets a bad reputation, but does it deserve it? It’s true that it’s a processed product, made from real cheese blended with emulsifiers to create that famously smooth, meltable texture. But not all American cheese is created equal. Some versions are closer to real cheese than others, with fewer additives and better flavor. Here are seven of the best American cheese slices made with real cheese, according to experts.
Tasty American Cheese Singles

These artisan-style singles emphasize flavor and sourcing, offering a more crafted take on American cheese. Nutritionally, they’re similar to others, with calcium and protein alongside saturated fat and sodium. But the focus on quality ingredients makes them a standout for anyone who appreciates a better-tasting slice.
Organic Valley American Cheese

Organic Valley’s slices use organic dairy, which appeals to shoppers focused on sourcing and production methods. From a nutrition standpoint, the calories, fat, and protein are similar to other American cheeses. The key difference is organic certification, not a major nutritional shift. If sourcing matters to you, this is a reliable pick.
Horizon Organic American Cheese

Horizon’s organic version provides comparable protein and calcium to other American cheeses. Like Organic Valley, the emphasis is on organic certification rather than a different nutritional profile. It’s a dependable option for those who prioritize organic dairy in their everyday purchases.
Sargento Natural American Cheese

Sargento’s “Natural” American is positioned closer to traditional cheese, meaning it may contain fewer stabilizers than standard singles. Nutritionally, it provides protein and calcium, but like most American slices, it also contributes sodium and saturated fat. It’s a solid choice for anyone wanting a less processed option without sacrificing meltability.
Kraft Deli Deluxe American Cheese

Kraft Deli Deluxe stands out because it often contains more real cheese in the blend, giving it a texture closer to natural cheese. The meltability is excellent, making it a favorite for burgers and grilled cheese. It still contributes saturated fat and sodium, so it’s best enjoyed in moderation, but for flavor and performance, it’s hard to beat.
Boar’s Head American Cheese

Boar’s Head is known for high-quality deli products, and their American cheese is no exception. It has a slightly firmer texture and offers protein similar to other brands. As with most deli cheeses, sodium can add up quickly, so portion awareness matters. But for a clean, flavorful slice, it’s a top contender.
Land O Lakes Sharp American Cheese

Land O Lakes offers a sharp American that delivers bolder flavor. The sharper profile may reflect a higher proportion of traditional cheese in the blend. Nutritionally, it’s comparable to other American slices, providing calcium but also saturated fat and sodium. If you want more flavor from your cheese, this is a great choice.
These seven options prove that American cheese can be more than just plastic-wrapped singles. Whether you prioritize organic sourcing, sharper flavor, or cleaner ingredients, there’s a slice here worth trying. Your grilled cheese deserves it.